Product Description
PE-22-28 is a synthetic heptapeptide analog derived from spadin, a naturally occurring peptide fragment of the sortilin protein. This shortened seven-amino-acid sequence represents the most active region of spadin and acts as a potent TREK-1 (TWIK-related potassium channel) inhibitor with an IC50 value of 0.12 nM.
Research investigations have examined PE-22-28 peptide in studies of two-pore potassium channel activity, serotonergic neuron firing rates, neurogenesis and synaptogenesis pathways, and CREB signaling mechanisms in neurological models. The compound is used in controlled laboratory environments for investigating mood regulation pathways, hippocampal neurogenesis, BDNF expression modulation, and neuroprotective mechanisms in cellular studies.
Supplied as pharmaceutical-grade spray with third-party verified purity testing for qualified research institutions conducting in vitro research applications only.
Our Product Quality Guarantee
Every Limitless Biotech Premium Lyophilized compound undergoes comprehensive independent third-party testing, including HPLC purity, sterility, endotoxin, and identity verification, as part of our systematic quality protocols.
Buy PE-22-28 Peptide From Limitless Biotech
Limitless Biotech provides USA-manufactured PE-22-28 for sale with verified molecular sequences and purity through comprehensive third-party testing. We ensure research quality with same-day shipping and dedicated customer support for your scientific endeavors.