DSIP Peptide
Aug 17th 2026
DSIP, short for Delta Sleep-Inducing Peptide, is a nine-amino-acid research peptide first characterized in rabbit experimental work. Its name reflects electroencephalogram findings reported in that early model, while its receptor identity and broader biological role remain unresolved.
For research use only. Not for human or animal use.
DSIP identity and research context
The DSIP sequence is Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. In the original 1977 rabbit model, synthetic DSIP was evaluated under controlled experimental conditions and was associated with changes in delta and spindle electroencephalogram patterns. The study was specific to that model and experimental design.
Later literature has discussed DSIP in relation to circadian, neuroendocrine, and stress-response research, but its natural occurrence, receptor identity, and broader biological role remain incompletely resolved. Proposed HPA-axis, GABAergic, cortisol, seizure, sleep, or stress mechanisms therefore remain unconfirmed rather than established product functions.
Taken together, the published record supports a cautious, model-specific description of DSIP centered on its defined sequence, historical EEG findings, and unresolved mechanism.
The Circadian Research selection provides a broader catalog pathway for materials associated with laboratory investigation of circadian models.
Product specifications and documentation
The current DSIP base product is listed as a Premium Lyophilized material with the following specifications:
- Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Molecular formula: C35H48N10O15
- CAS number: 62568-57-4
- PubChem CID: 68816
- Physical appearance: white lyophilized powder
- Storage specification: -20°C, tightly sealed and protected from heat and moisture
- Shelf-life specification: 36 months from manufacture when stored according to the product record
- Minimum purity specification: at least 99% for the Premium Lyophilized line
The public COA section includes purity, sterility, and endotoxin reports for applicable Premium Lyophilized lots. The current matching COA provides the batch-specific results, while professional pricing is available after research-account approval and login.
Base product and spray-format relationship
The base DSIP record covers the compound’s identity and the specifications for the lyophilized product. The DSIP Spray record covers its separate package and may reference analytical documentation for the underlying DSIP material and grade. Because the compound identity remains the same across formats, researchers can compare package, storage, and documentation details on the relevant product record.
Frequently asked questions
What is DSIP?
DSIP is a synthetic nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. Its name comes from early rabbit EEG research and does not establish a human effect.
What does the published DSIP evidence show?
The original study reported changes in delta and spindle EEG patterns in a controlled rabbit model. Broader mechanisms and roles remain uncertain, so proposed sleep, stress, endocrine, or neurotransmitter effects should not be stated as settled conclusions.
How does the base DSIP page differ from DSIP Spray?
The base record covers generic compound identity and the Premium Lyophilized material. The spray record covers a separate supplied format. Both identify the applicable underlying-material COA and research-only restrictions.
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